In ESRD, what is a common anemia treatment and its effect?

• A. Erythropoiesis-stimulating agents (ESAs) with iron supplementation to raise hemoglobin and reduce fatigue
• B. Vitamin B12 injections to increase energy
• C. Calcium supplements to raise hemoglobin
• D. Diuretics to reduce fatigue

Answer: (A)

In ESRD, anemia stems from the kidneys producing less erythropoietin, so the body can’t make enough red blood cells. The effective treatment is to use an erythropoiesis-stimulating agent to boost red blood cell production and to provide iron when stores are low, since iron is essential for making new cells. Together, this approach raises hemoglobin and improves oxygen delivery to tissues, which often reduces fatigue and the sense of low energy. In dialysis patients, iron is commonly given intravenously during treatment, and the ESA dose is carefully adjusted to reach a safe hemoglobin level without overshooting.

Vitamin B12 injections target B12 deficiency anemia, not the typical ESRD-related anemia. Calcium supplements address mineral balance, not red blood cell production. Diuretics help with fluid overload and blood pressure but do not raise hemoglobin.